About Ferritin
Ferritin is a ubiquitous intracellular protein that stores iron and releases it in a controlled fashion. It acts as a buffer against iron deficiency and iron overload. Measuring ferritin levels in the blood provides an indirect estimate of the total iron stores in the body, making it crucial for assessing iron-related disorders.
Reference Values
Health Implications
{'high': 'Elevated levels may indicate conditions such as hemochromatosis, which can lead to organ damage if left untreated, or chronic inflammatory disorders.', 'low': 'Low levels may be associated with iron deficiency anemia, resulting in fatigue, weakness, and impaired cognitive function.'}
Symptoms
{'high': 'May include fatigue, joint pain, stomach pain, and palpitations.', 'low': 'Can include fatigue, dizziness, weakness, and rapid heartbeat.'}
Lifestyle Factors
Specimen Type
Testing Methods
Scientific Sources
- Camaschella, C. (2019). Iron-deficiency anemia. *New England Journal of Medicine*, 381(11), 1148-1157.|Kell, D. B., & Pretorius, E. (2018). No effects without causes: The iron dysregulation and dormant microbes hypothesis for chronic, inflammatory diseases. *Biological Reviews*, 93(3), 1518-1557.|World Health Organization. (2020). Serum ferritin concentrations for the assessment of iron status and iron deficiency in populations. *WHO Guidelines*.|Ganz, T., & Nemeth, E. (2020). Iron homeostasis in host defence and inflammation. *Nature Reviews Immunology*, 20(7), 392-400.|Camaschella, C. (2017). Iron-deficiency anemia. *New England Journal of Medicine*, 377(1), 54-63.