About hsCRP
High-sensitivity C-reactive protein (hsCRP) is a biomarker of systemic inflammation. It is a protein produced by the liver in response to inflammation. Measuring hsCRP levels can help assess cardiovascular disease risk, as chronic inflammation is associated with atherosclerosis and other cardiovascular problems.
Reference Values
Optimal Range
0 - 1 mg/dL
Elite Value
Not specified
Health Implications
High
Elevated levels may indicate an increased risk of cardiovascular diseases, inflammation, or infection in the body.
Low
Low levels may be associated with a reduced risk of heart diseases but could also indicate issues with the liver or lower immune function.
Symptoms
High
May include fatigue, headaches, muscle pain, joint pain, chest pain, unexplained weight loss, sweating, and rapid heartbeat.
Low
Can include dizziness, weakness, fainting, sleep disturbances, and confusion.
Lifestyle Factors
Specimen Type
Testing Methods
Also Known As
Scientific Sources
- dker, P. M., & Everett, B. M. (2019). C-reactive protein and atherothrombosis: Twenty years of discovery and progress. Circulation, 139(16), 1871–1886.
- arson, T. A., Mensah, G. A., Alexander, R. W., Anderson, J. L., Cannon, R. O., Criqui, M., ... & Vinicor, F. (2003). Markers of inflammation and cardiovascular disease: Application to clinical and public health practice: A statement for healthcare professionals from the Centers for Disease Control and Prevention and the American Heart Association. Circulation, 107(3), 499–511.
- erging Risk Factors Collaboration. (2010). C-reactive protein concentration and risk of coronary heart disease, stroke, and mortality: An individual participant meta-analysis. The Lancet, 375(9709), 132–140.
- dker, P. M., Danielson, E., Fonseca, F. A., Genest, J., Gotto, A. M., Kastelein, J. J., ... & JUPITER Study Group. (2008). Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein. New England Journal of Medicine, 359(21), 2195–2207.
- ptoge, S., Di Angelantonio, E., Lowe, G., Pepys, M. B., Thompson, S. G., Collins, R., ... & Danesh, J. (2010). C-reactive protein concentration and risk of coronary heart disease, stroke, and mortality: An individual participant meta-analysis. The Lancet, 375(9709), 132–140.