About IGF-1
Insulin-like growth factor 1 (IGF-1) is a protein hormone akin to insulin, primarily produced by the liver, that plays an important role in childhood growth and continues to have anabolic effects in adults. It is influenced by growth hormone (GH) levels and is involved in various cellular processes including cell proliferation, differentiation, and apoptosis.
Reference Values
Optimal Range
Not specified
Elite Value
Not specified
Health Implications
High
Elevated levels may indicate an increased risk of developing conditions like acromegaly, certain cancers, and insulin resistance.
Low
Low levels may be associated with growth deficiencies, muscle weakness, and hormonal imbalances affecting overall health.
Symptoms
High
May include headache, joint pain, excessive sweating, and rapid irregular growth.
Low
Can include fatigue, reduced muscle mass, low energy levels, and increased fat deposition.
Lifestyle Factors
Specimen Type
Testing Methods
Also Known As
Scientific Sources
- | Clemmons, D. R. (2020). Role of IGF-I in skeletal muscle mass maintenance. Trends in Endocrinology & Metabolism, 31(5), 335-347.
- Yakar, S., & Adamo, M. L. (2018). Insulin-like growth factor-1 physiology: lessons from mouse models. Endocrinology and Metabolism Clinics, 47(2), 231-248.
- Livingstone, C., & Borai, A. (2014). Insulin-like growth factor-II: its role in metabolic and endocrine disease. Clinical Endocrinology, 80(6), 773-781. |