About Lipoprotein Fractionation
Lipoprotein fractionation is a laboratory test that separates lipoproteins in the blood into their components, such as high-density lipoprotein (HDL), low-density lipoprotein (LDL), very low-density lipoprotein (VLDL), chylomicrons, and others. This test is used to provide a detailed profile of lipid particles in the blood, which is useful for assessing cardiovascular disease risk.
Reference Values
Optimal Range
Not specified
Elite Value
Not specified
Health Implications
High
Elevated levels may indicate an increased risk of cardiovascular disease and potential inflammation in the arteries.
Low
Low levels may be associated with impaired cell membrane production or decreased fat transport, which can affect overall metabolic functions.
Symptoms
High
May include chest pain, shortness of breath, and fatigue.
Low
Can include dizziness, weakness, and fainting.
Lifestyle Factors
Specimen Type
Testing Methods
Also Known As
Scientific Sources
- Sniderman, A. D., Thanassoulis, G., Glavinovic, T., Navar, A. M., Pencina, M., & Catapano, A. L. (2019). Apolipoprotein B Particles and Cardiovascular Disease: A Narrative Review. JAMA Cardiology, 4(12), 1287–1295.
- Toth, P. P., Fazio, S., Wong, N. D., Hull, M., Nichols, G. A., & Risk Assessment Working Group. (2019). Risk Stratification for Primary Prevention of Atherosclerotic Cardiovascular Disease: A Review of Current Practice and Recommendations for Improvement. Journal of the American Heart Association, 8(15), e011461.
- Grundy, S. M., Stone, N. J., Bailey, A. L., Beam, C., Birtcher, K. K., Blumenthal, R. S., ... & Yeboah, J. (2019). 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Blood Cholesterol: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. Circulation, 139(25), e1082–e1143.
- Catapano, A. L., Graham, I., De Backer, G., Wiklund, O., Chapman, M. J., Drexel, H., ... & Reiner, Ž. (2016). 2016 ESC/EAS Guidelines for the Management of Dyslipidaemias. European Heart Journal, 37(39), 2999–3058.
- Jellinger, P. S., Handelsman, Y., Rosenblit, P. D., Bloomgarden, Z. T., Fonseca, V. A., Garber, A. J., ... & Smith, D. (2017). American Association of Clinical Endocrinologists and American College of Endocrinology Guidelines for Management of Dyslipidemia and Prevention of Cardiovascular Disease. Endocrine Practice, 23(Suppl 2), 1–87.