About oxLDL
Oxidized LDL (low-density lipoprotein) is a form of cholesterol that has been modified by oxidation. It is a key player in the development of atherosclerosis, as it contributes to the formation of plaques within arterial walls. OxLDL is considered more atherogenic than native LDL because it is taken up by macrophages to form foam cells, a critical step in plaque formation and vascular inflammation.
Reference Values
Optimal Range
0.0 - 20.0 ng/mL
Elite Value
Not specified
Health Implications
High
Elevated levels may indicate a higher risk of developing atherosclerosis, potentially leading to cardiovascular diseases such as heart attacks and strokes.
Low
Low levels may be associated with a reduced risk of oxidative damage and cardiovascular issues, though it might also suggest potential disruptions in lipid metabolism.
Symptoms
High
May include fatigue, chest pain, and shortness of breath due to potential arterial inflammation. Other symptoms might be headaches, unexplainable fatigue, and changes in skin color due to reduced blood flow.
Low
Can include dizziness, overall weakness, trouble concentrating, and cold extremities due to reduced cholesterol and blood energy levels.
Lifestyle Factors
Specimen Type
Testing Methods
Also Known As
Scientific Sources
- Luquain-Costaz, C., & Delton, I. (2024). Oxysterols in Vascular Cells and Role in Atherosclerosis. arXiv preprint arXiv:2409.15874.
- Authors: Celine Luquain-Costaz, Isabelle Delton. (2024). Oxysterols in Vascular Cells and Role in Atherosclerosis. arXiv preprint arXiv:2409.15874.
- Luquain-Costaz, C., & Delton, I. (2024). Oxysterols in Vascular Cells and Role in Atherosclerosis. arXiv preprint arXiv:2409.15874.