About Mean Platelet Volume (MPV)
Mean Platelet Volume (MPV) is a measure of the average size of platelets in the blood and is a component of complete blood count (CBC) tests. It provides an indication of platelet production in bone marrow. Larger platelets are generally younger and potentially more reactive, being indicative of various physiological and pathological processes.
Reference Values
Optimal Range
7.5 - 10.5 fL
Women's Optimal Range
7.5 - 10.5 fL
Elite Value
Not specified
Health Implications
High
Elevated levels may indicate an increased risk of cardiovascular diseases or a recent platelet activation caused by inflammation or other blood disorders.
Low
Low levels may be associated with bone marrow disorders, certain types of anemia, or underlying thrombocytopenia, impacting blood clot formation.
Symptoms
High
May include fatigue, headaches, and bruising.
Low
Can include dizziness, weakness, and pale skin.
Lifestyle Factors
Specimen Type
Testing Methods
Also Known As
Scientific Sources
- Gasparyan, A. Y., Ayvazyan, L., Mikhailidis, D. P., & Kitas, G. D. (2011). Mean platelet volume: a link between thrombosis and inflammation? *Current Pharmaceutical Design*, 17(1), 47–58.
- Papanas, N., Symeonidis, G., Maltezos, E., & Mikhailidis, D. P. (2010). Mean platelet volume in patients with type 2 diabetes mellitus. *Platelets*, 21(2), 118–123.
- Chu, S. G., Becker, R. C., Berger, P. B., Bhatt, D. L., Eikelboom, J. W., Konkle, B., Mohler, E. R., Reilly, M. P., & Berger, J. S. (2010). Mean platelet volume as a predictor of cardiovascular risk: a systematic review and meta-analysis. *Journal of Thrombosis and Haemostasis*, 8(1), 148–156.
- Bath, P. M., & Butterworth, R. J. (1996). Platelet size: measurement, physiology and vascular disease. *Blood Coagulation & Fibrinolysis*, 7(2), 157–161.
- Noris, P., & Balduini, C. L. (2012). Mean platelet volume and risk: the clinical perspective. *Arteriosclerosis, Thrombosis, and Vascular Biology*, 32(1), 4–6.