About Leptin
Leptin is a hormone predominantly made by adipose cells and the small intestine that regulates energy balance by inhibiting hunger, which in turn helps to regulate body weight. It plays a role in the regulation of appetite and metabolism, conveying information on energy status to the hypothalamus in the brain.
Reference Values
Optimal Range
Not specified
Elite Value
Not specified
Health Implications
High
Elevated levels may indicate leptin resistance, which is often associated with obesity and can lead to difficulties in weight management and increased risk of cardiovascular diseases.
Low
Low levels may be associated with conditions such as primary hypogonadism, and could lead to problematic weight gain, reduced energy expenditure, and issues with appetite regulation.
Symptoms
High
May include weight gain, difficulty losing weight, fatigue, cravings for carbohydrates, and increased hunger.
Low
Can include fatigue, difficulty concentrating, reduced immune function, irritability, and potential weight gain due to hunger.
Lifestyle Factors
Specimen Type
Testing Methods
Also Known As